L-dopa - MSDS

2 - Product Identification Data
Trade Name: L-Dopa
CAS Nº: 57-92-7
Synonyms: 3-(3,4 Dihydroxyphenil)-L-alanine
EINECS #: 200-445-2
Chemical Name: 1-Dihydroxyphenyl-1-alanine
Formulary: ---
Chemical Classification: Amino acid
 
3 - Hazards Identification
Causes respiratory tract irritation. May cause digestive tract irritation. Light sensitive. Air sensitive. May be harmful if swallowed. Causes eyes and skin irritation.
Target Organs: Heart, central nervous system.

Potential Health Effects
Eye: Causes eye irritation.

Skin: Cause skin irritation.

Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed. May cause central nervous system effects such as psychosis, hallucinations, depression, visual changes and mental changes. May cause cardiac abnormalities.

Inhalation: Cause respiratory tract irritation.

Chronic: Chronic ingestion may cause effects similar to those of acute ingestion. May cause reproductive and fetal effects.
 
4 - First aid measures
Eyes: Immediately flush eyes with plenty of water at least 15 minutes, occasionally lifting the upper and lower lids. Get medical aid immediately.
Skin: Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Remove to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: treat symptomatically and supportively.
 
5 - Fire and explosion hazard data
Extinguishing Media: In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam..
Protective Equipment: self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Autoignition Temperature: Not available.
Flash Point: Not available.
NFPA Rating: Not published.
Explosion Limits
Lower: Not available.
Upper: Not available.

6 - Spill or leak procedures
Personal precautions: Use proper personal protective equipment as indicated in Section 8
Environmental precautions: None
Methods for cleaning up: Vacuum or sweep up material and place into a suitable disposal container. Clear up spills immediately, observing precautions in the protective equipment section. Avoid generating dusty conditions.
 
7 - Handling and storage
Handling: Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage: Storage in a cool, dry place. Keep from container closed when not in use. Absorbs oxygen from the air and will darken upon exposure. Store protected from light.
 
8 - Exposure controls, personal protection
Exposure Limits
ACGIH: None listed
NIOSH: None listed
OSHA - FINAL PELs: None listed
OSHA Vacated PELs: None listed
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical Safety goggles as described by OSHA¢s eye and face Protection regulations in 29 CFR 1910. 133 or European Standard EN166.
Skin: Wear appropriate gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910. 134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Engineering Controls: Use adequate ventilation to keep airborne concentrations low.
 
9 - Physical and Chemical properties

Physical State: Powder or crystalline powder
Appearance: White to slightly cream powder
Odor: odorless
Ph: Not available.
Vapor Pressure: Not available
Vapor Density: Not available.
Evaporation Rate: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Melting Point: 295ºC
Decomposition Temperature: Not available.
Solubility: Not available
Specific Gravity/Density: Not available
Molecular Formula: C9H11NO4
Molecular Weight: 197.19
 
10 - Stability and reactivity
Stability: Stable under temperatures and pressures.
Conditions to Avoid: incompatible materials, light, exposure to air.
Incompatibilities with other materials: Strong oxidizing agents.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
 
11 – Toxicological InformationRTECS#
CAS# 59-92-7: AY5600000
LD50/LC50
Oral, rat: LD50 = 1780 mg/kg.
Carcinogenicity: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Experience in Humans: Not available.
 
12 – Ecological InformationEcotoxicity: Not available.
Environmental fate: Not available.
Other: Not available.
 
13 - Transport Information
US DOT: No information available
IMO: Not regulated as a hazardous material
IATA: No regulated as a hazardous material
RID/ADR: No regulated as a hazardous material
Canadian TDG: No information available.
 
14 - Disposal considerations
Dispose of in a manner consistent with federal, state, and local regulations.
RCRA D-Series Maximum Concentration of Contaminants: None listed.
RCRA D-Series Chronic Toxicity Reference Levels: None listed.
RCRA F-Series: None listed.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Not listed as a material banned land disposal according to RCRA.

15 – REGULATORY INFORMATIONUS FEDERAL
TSCA:
CAS# 59-92-7 is not listed on the TSCA Inventory.
Health & Safety Reporting List:
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rule:
None of the chemicals in this product are under Chemical Test Rule.
Section 12b:
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule:
None of the chemicals in this material have a SNUR under TSCA.
SARA
Section 302 (RQ):
None of the chemicals in this material have na RQ.
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
Section 313
No chemical are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 ozone depletors.
This material does not contain any Class 2 ozone depletors.
Clean water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants Under the CWA.
OSHA:
None of the chemicals in this products are considered highly hazardous by OSHA.
STATE:
L-Dopa, 99% is not present on state lists from CA, PA, MN MA, FL,or NJ.
California No Significant Risk Level:
None of the chemicals in this products are listed.
European/International Regulations:
European Labeling in Accordance with EC Directives
Hazard Symbols: XN XI
Risk Phrases:
R 22 Harmful if swallowed.
R 33 Danger or cumulative effects
R36/37/38 Irritating to eyes, respiratory system and skin.
Safety Phrases:
S24/25 Avoid contact with skin and eyes.
S 36/37/38 Wear suitable protective clothing, gloves and eye / face protection.
WGK (Water Danger/Protection):
CAS# 59 -92 - 7: No information available.
Canada:
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 59-92-7 is not listed on Canada¢s Ingredient Disclosure List.
 
Section 16 – Additional Information
The information contained in this document is based on the present state of our knowledge. However we give no warranty for completeness. We would like to point out that this data sheet is mend to be a guide for users but not an ultimate manual. Users should make their own investigations to determine the suitability of the provided information for their particular purposes. In any case the user has to consider current laws and regulations.
In no way PVP S.A. shall be liable for any claims, losses or damages of any third party caused by the use of information given in this material safety data sheet.